A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction

Launched by CENTRE HOSPITALIER UNIVERSITAIRE, AMIENS · Apr 4, 2019

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help doctors decide how to treat patients with a condition called adhesion-related small bowel obstruction (ASBO). ASBO happens when the intestines get blocked due to scar tissue from previous surgeries. Doctors can choose to treat this condition either without surgery or with an operation, but it can be hard to know the best choice. In this trial, researchers are looking at a method that uses a blood test for a substance called procalcitonin to guide treatment decisions.

To be part of this trial, participants need to be adults aged 65 to 74 who have uncomplicated acute ASBO and can give consent. They should also be covered by national health insurance. Those who have had recent abdominal surgery, certain types of cancer, or other specific health conditions will not be eligible. If someone joins the trial, they will undergo tests and evaluations to see how well the procalcitonin-based approach works in managing their condition. This research aims to improve treatment options and outcomes for patients facing this common digestive emergency.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Uncomplicated acute adhesion-related small bowel obstruction (ASBO)
• • Adults
• • Patients able to express consent
• • Signed written informed consent form
• • Covered by national health insurance
• Exclusion Criteria:
• * Disease-related criteria:
• • Large bowel obstruction
• • No previous abdominal surgery
• • Signs of peritonitis or strangulation requiring emergency surgery)
• • Obstruction within 4 weeks following previous surgery
• • Ongoing or history of bowel cancer
• • Ongoing or in history of inflammatory bowel disease
• • History of abdominal radiotherapy
• • Active infection
• • Contraindication to contrast-enhanced CT scan
• • Minors
• • Patient deprived of liberty by administrative or judicial decision or placed under judicial protection (guardianship or supervision)
• • Pregnancy or breastfeeding