Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia
Launched by WRIGHT STATE UNIVERSITY · Apr 5, 2019
Trial Information
Current as of June 27, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how effective a treatment called fractionated laser resurfacing (FLR) is in helping older adults with skin issues caused by sun exposure, specifically actinic keratosis, which can lead to non-melanoma skin cancer. The goal is to see if treating one forearm with FLR can quickly remove these skin spots and help prevent more from developing over time compared to the untreated forearm. Researchers have found that FLR has lasting benefits for at least two years, and this study will help confirm those findings over a longer period.
To participate, you need to be at least 60 years old and have been diagnosed with actinic keratosis within the last six months. You should also have fair skin and be able to understand the study's procedures and risks. The study will take place over five years, starting with a single treatment day followed by follow-up visits at three months and every six months after that. It's important to note that some people may not be eligible, such as those with uncontrolled diabetes or certain skin conditions. If you think you might qualify and are interested in helping advance skin care for older adults, this trial could be a great opportunity!
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Diagnosed with Actinic Keratosis within the past 6 months
- • At least 60 years of age, or older
- • Ability to comprehend procedures and risks versus benefits
- • Able to provide Informed Consent
- • Fair Skin (Fitzpatrick Type I or II)
- • Possess both Right and Left Forearms
- Exclusion Criteria:
- • Uncontrolled Diabetes Mellitus
- • Not able to comprehend procedures or risks versus benefits
- • Pregnant or nursing
- • Large tattoos on forearms
- • History of abnormal healing or scarring (i.e., keloids)
- • Any disease that gets worse while in the sun
- • Use of topical or oral anti-inflammatory medication or steroids
- • Allergy to lidocaine
- • Current use of photosensitizing medication
About Wright State University
Wright State University is a distinguished academic institution located in Dayton, Ohio, renowned for its commitment to advancing healthcare through innovative research and education. As a clinical trial sponsor, the university leverages its extensive resources and expertise in various medical fields to conduct rigorous clinical studies aimed at improving patient outcomes and contributing to the broader scientific community. With a multidisciplinary approach, Wright State University collaborates with healthcare professionals, researchers, and industry partners to ensure the integrity and efficacy of its trials, ultimately striving to translate research findings into actionable clinical practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Dayton, Ohio, United States
Patients applied
Trial Officials
Jeffrey B Travers, MD, PhD
Principal Investigator
Wright State University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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