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Search / Trial NCT03919838

Effect of Probiotic on Oral Health of Children

Launched by MEDICAL UNIVERSITY OF WARSAW · Apr 17, 2019

Trial Information

Current as of July 21, 2025

Unknown status

Keywords

Probiotic Oral Health Children

ClinConnect Summary

Probiotic bacteria are used in the prevention and treatment of gastrointestinal diseases and infections, including the treatment of oral diseases. Probiotic bacteria can be found in saliva, plaque and adhering directly to the mucous membrane. They compete with cariogenic bacteria and pathogens of periodontal disease. Increased interest in probiotics means that attempts are being made to find new solutions regarding the methods of their administration. The use of probiotic bacteria brings beneficial health effects. Lactobacillus salivarius is a strain isolated from human milk. It is inactive...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • generally healthy children aged 3-6;
  • recognized caries of early childhood, dmf\> 1,
  • lack of active caries and inflammation of the mouth
  • colony forming unit CFU \> 105 / ml Streptococcus mutans
  • a minimum of one-month period from: the last antibiotic therapy, probiotic use, professional fluoride prophylaxis or supervised tooth brushing with fluoride preparations, the use of fluoride toothpaste, not using xylitol, written consent of parents / legal guardians for participation in research.
  • Exclusion Criteria:
  • chronic diseases and chronically taken medicines in the past,
  • planned change of residence during the year,
  • age below 3 and above 6 years,
  • healthy teeth, dmf = 0,
  • colony forming unit CFU \<105 / ml Streptococcus mutans
  • Patient during antibiotic therapy, probiotic use, professional fluoride prophylaxis or supervised tooth brushing with fluoride preparations
  • no toothpaste with fluoride
  • using xylitol
  • lack of written consent of parents / legal guardians for participation in research.

About Medical University Of Warsaw

The Medical University of Warsaw is a leading academic institution dedicated to advancing healthcare through innovative research and education. Renowned for its commitment to excellence in medical training and clinical practice, the university actively engages in a diverse range of clinical trials aimed at improving patient outcomes and enhancing medical knowledge. With a robust infrastructure and a multidisciplinary team of experts, the Medical University of Warsaw fosters collaboration in the development of novel therapies and interventions, contributing significantly to the global medical research landscape.

Locations

Warsaw, , Poland

Warsaw, , Poland

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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