Effect of Probiotic on Oral Health of Children
Launched by MEDICAL UNIVERSITY OF WARSAW · Apr 17, 2019
Trial Information
Current as of July 21, 2025
Unknown status
Keywords
ClinConnect Summary
Probiotic bacteria are used in the prevention and treatment of gastrointestinal diseases and infections, including the treatment of oral diseases. Probiotic bacteria can be found in saliva, plaque and adhering directly to the mucous membrane. They compete with cariogenic bacteria and pathogens of periodontal disease. Increased interest in probiotics means that attempts are being made to find new solutions regarding the methods of their administration. The use of probiotic bacteria brings beneficial health effects. Lactobacillus salivarius is a strain isolated from human milk. It is inactive...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • generally healthy children aged 3-6;
- • recognized caries of early childhood, dmf\> 1,
- • lack of active caries and inflammation of the mouth
- • colony forming unit CFU \> 105 / ml Streptococcus mutans
- • a minimum of one-month period from: the last antibiotic therapy, probiotic use, professional fluoride prophylaxis or supervised tooth brushing with fluoride preparations, the use of fluoride toothpaste, not using xylitol, written consent of parents / legal guardians for participation in research.
- Exclusion Criteria:
- • chronic diseases and chronically taken medicines in the past,
- • planned change of residence during the year,
- • age below 3 and above 6 years,
- • healthy teeth, dmf = 0,
- • colony forming unit CFU \<105 / ml Streptococcus mutans
- • Patient during antibiotic therapy, probiotic use, professional fluoride prophylaxis or supervised tooth brushing with fluoride preparations
- • no toothpaste with fluoride
- • using xylitol
- • lack of written consent of parents / legal guardians for participation in research.
About Medical University Of Warsaw
The Medical University of Warsaw is a leading academic institution dedicated to advancing healthcare through innovative research and education. Renowned for its commitment to excellence in medical training and clinical practice, the university actively engages in a diverse range of clinical trials aimed at improving patient outcomes and enhancing medical knowledge. With a robust infrastructure and a multidisciplinary team of experts, the Medical University of Warsaw fosters collaboration in the development of novel therapies and interventions, contributing significantly to the global medical research landscape.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Warsaw, , Poland
Warsaw, , Poland
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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