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Search / Trial NCT03925714

Impact of P53 and SIRT1 in Type 2 Diabetes

Launched by SHERIEF ABD-ELSALAM · Apr 22, 2019

Trial Information

Current as of July 05, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at how two specific proteins, p53 and SIRT1, might affect the development of type 2 diabetes. Researchers want to understand if these proteins play a role in helping people who are at risk of developing diabetes, specifically those who are in a prediabetic state. This means they have higher than normal blood sugar levels but are not yet diagnosed with diabetes.

To join the study, participants should be between the ages of 65 and 74 and currently in a prediabetic condition. However, individuals with confirmed diabetes or those with liver or kidney problems cannot take part in this trial. If you join, you can expect to undergo various tests and assessments to help researchers gather important information about how p53 and SIRT1 might influence blood sugar levels. This study is currently actively seeking participants, so if you fit the criteria and are interested, it could be a great opportunity to contribute to important diabetes research.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Prediabetic subjects.
  • Exclusion Criteria:
  • Confirmed diabetes.
  • Hepatic or renal impairment.

About Sherief Abd Elsalam

Sherief Abd-elsalam is a dedicated clinical trial sponsor with extensive expertise in advancing medical research and innovation. Committed to improving patient outcomes, Abd-elsalam oversees the design, implementation, and management of clinical trials across various therapeutic areas. With a strong focus on regulatory compliance and ethical standards, he fosters collaboration between research institutions, healthcare professionals, and regulatory bodies to ensure the successful progression of trials. Abd-elsalam's leadership is characterized by a commitment to scientific integrity and a passion for translating research findings into actionable healthcare solutions.

Locations

Cairo, , Egypt

Patients applied

0 patients applied

Trial Officials

Eman SA Sawan, Msc

Principal Investigator

Tanta University - Faculty of Pharmacy

Sahar Hegazy, Prof

Principal Investigator

Tanta University - Faculty of Pharmacy

Tarek Mostafa, ass. Prof.

Study Director

Tanta University - Faculty of Pharmacy

Sherin El-Nidany, MD

Study Chair

Tanta University-Faculty of pharmacy

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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