Normotensive OSA Patients With Dipper Circadian Blood Pressure Pattern

Launched by SOCIEDAD ESPAÑOLA DE NEUMOLOGÍA Y CIRUGÍA TORÁCICA · May 10, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how a treatment called CPAP (Continuous Positive Airway Pressure) affects blood pressure in patients who have sleep apnea but are not currently experiencing high blood pressure. The main goal is to see if using CPAP helps lower blood pressure in people who have a specific sleeping pattern known as a "dipper circadian pattern." Additionally, the researchers want to understand how often different blood pressure patterns occur, how well patients stick to using the CPAP, and what changes happen in certain blood markers during treatment.

To participate in this study, you need to be an adult over 18 years old, referred for suspected sleep apnea, and have a specific level of severity in your sleep study. You'll be randomly assigned to either receive CPAP treatment or a different kind of care. Participants will undergo blood pressure monitoring and provide blood samples at the start of the study and again after three months. This trial is currently recruiting participants, and it's important to note that those with certain health conditions or previous CPAP use are not eligible. If you’re interested or think you might qualify, talk to your healthcare provider for more information.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Men and women over 18 years of age
• • 2. Referred to the sleep unit for suspected OSA
• • 3. Being normotensive and presenting an AHI ≥ 30 in the sleep study
• • 4. Signature of the informed consent.
• Exclusion Criteria:
• • 1. Previous CPAP treatment
• • 2. Significant somnolence defined by an Epworth Sleepiness Scale (ESS) score higher than 18
• • 3. Psychophysical inability to complete questionnaires
• • 4. Previous diagnosis or suspicion of another sleep disorder
• • 5. Presence of more than 50% of central apneas or Cheyne-Stokes respiration
• • 6. Having a serious chronic disease: neoplasia, renal failure, severe chronic obstructive pulmonary disease, chronic depression and other chronic limiting diseases
• • 7. Medical history that may interfere with the objectives of the study or, in the opinion of the researcher, may compromise the conclusions
• • 8. Any medical, social or geographical factor that may endanger the patient's compliance 9-Having a profession of high risk (professional driver).