PARQuit Smoking Cessation Intervention for Adults With Serious Mental Illness

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · May 13, 2019

Keywords

ClinConnect Summary

The PARQuit study is researching a special program designed to help adults with serious mental illness (SMI) quit smoking. This program combines fun video game-based physical activities, counseling to support quitting smoking, and a medication called bupropion, which can help reduce cravings. The goal is to see how effective this approach is for people who smoke regularly and are dealing with mental health challenges.

To be part of this study, participants need to be at least 18 years old, have a diagnosis of serious mental illness, and have been smoking at least five cigarettes a day for the past six months. They should also be willing to choose a quit date and be currently involved in a Progress Foundation treatment program. If you or someone you know meets these criteria, there is a chance to join this important study. Participants will engage in the program for about 12 weeks and will receive support to help them successfully quit smoking while managing their mental health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A diagnosis of a SMI\*
• • 18 years and older
• • Smoking at least five cigarettes per day for the past 6 months
• • Willingness to set a quit date
• • Not currently taking bupropion or using nicotine replacement therapy (NRT)
• • Current participant in the residential or day treatment program at a Progress Foundation program with the intention to continue in the residential or day treatment program for at least the 12 week intervention period
• • Capacity to consent.
• • SMI is characterized by the American Psychological Association as distinct conditions that require routine management, produce functional impairment, and interfere with quality of life. Individuals that typically meet the criteria of SMI have illnesses that include schizophrenia, schizoaffective disorder, psychotic disorders, major depressive disorders, bipolar disorders, and borderline personality disorder.
• Exclusion Criteria:
• • Currently pregnant or breastfeeding
• • Diagnosis of seizure disorder, history of anorexia/bulimia, undergoing abrupt discontinuation of ethanol or sedatives, other conditions that increase seizure risk (e.g., arteriovenous malformation (AVM), severe head injury, central nervous system (CNS) tumor)
• • use of Monoamine oxidase (MAO) inhibitors (concurrently or within 14 days of discontinuing either bupropion or the MAO inhibitor)
• • Planning to become pregnant during the study period
• • Previous participation in the videogame-based physical activity intervention.
• • Known medical conditions or other physical problems that need special attention in an exercise program (e.g. prior myocardial infarction, uncontrolled hypertension, history of angioplasty, history of angina, use of nitroglycerin to treat angina)