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Search / Trial NCT03956251

Ridge Preservation With Putty Allografts

Launched by UNIVERSITY OF LOUISVILLE · May 16, 2019

Trial Information

Current as of July 06, 2025

Completed

Keywords

ClinConnect Summary

Thirty patients will be treated using the principles of guided bone regeneration utilizing a full thickness flap for ridge preservation. Fifteen test patients will receive an intrasocket demineralized and mineralized combination putty allograft (MinerOss Putty, BioHorizons) covered with a regenerative tissue matrix membrane (AlloDerm GBR, BioHorizons). The positive control group of fifteen patients will receive an intrasocket demineralized putty allograft (Puros, Zimmer) covered with a regenerative tissue matrix membrane (AlloDerm GBR, BioHorizons). Approximately, four months post-surgery, ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. Have one non-molar tooth requiring extraction that will be replaced by a dental implant. The site must be bordered by at least one tooth.
  • 2. Healthy male or female who is at least 18 years old.
  • 3. Patients must sign an informed consent approved by the University of Louisville Human Studies Committee.
  • Exclusion Criteria:
  • 1. Patients with debilitating systemic diseases, or diseases that have a clinically significant effect on the periodontium.
  • 2. Presence or history of osteonecrosis of jaws.
  • 3. Patients who are currently taking IV bisphosphonates or who had IV treatment with bisphosphonates irrespective of duration.
  • 4. Patients who have been treated with oral bisphosphonates for more than three years.
  • 5. Patients with an allergy to any material or medication used in the study.
  • 6. Patients who need prophylactic antibiotics
  • 7. Previous head and neck radiation therapy.
  • 8. Chemotherapy in the previous 12 months.
  • 9. Patients on long term NSAID or steroid therapy.
  • 10. Pregnant or lactating patients.

About University Of Louisville

The University of Louisville is a distinguished academic institution known for its commitment to advancing medical research and clinical innovation. As a clinical trial sponsor, the university leverages its extensive resources and expertise to conduct pioneering studies that aim to improve patient outcomes and enhance healthcare practices. With a focus on interdisciplinary collaboration and community engagement, the University of Louisville fosters an environment conducive to groundbreaking research across various medical fields, ensuring adherence to the highest ethical standards and regulatory compliance. Through its clinical trials, the university seeks to translate scientific discoveries into tangible benefits for patients and the broader community.

Locations

Louisville, Kentucky, United States

Patients applied

0 patients applied

Trial Officials

Henry Greenwell, DMD MSc

Principal Investigator

University of Louisville

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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