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Search / Trial NCT03956901

Goal Directed Fluid Management , Pvi

Launched by BAKIRKOY DR. SADI KONUK RESEARCH AND TRAINING HOSPITAL · May 17, 2019

Trial Information

Current as of May 02, 2025

Completed

Keywords

ClinConnect Summary

Objectives: The first objective of the investigators's study was to compare the liberal fluid management (LFM) with PVI guided goal-directed fluid management (GDFM) in terms of controlled intraoperative fluid volume, surgical end-point fluid balance, blood lactate and serum creatinine levels.

The investigators's secondary purpose was to compare the effects of different fluid regimens on the postoperative kidney injury and the duration of hospital stay.

Methods: The study included 112 American Society of Anesthesiologists (ASA) grade I ,ll and lll patients, aged above 18 and undergoing ele...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • 1. Gynecological oncologic cases
  • 2. Patients over 18 years old
  • 3. ASA 1-2-3 patients
  • Exclusion Criteria:
  • 1. Patients with peripheral arterial disease
  • 2. Patients with non-sinus rhythm, arrhythmia, atrial fibrillation
  • 3. Patients with entry MAP \<65 mmHg
  • 4. Patients with advanced renal and hepatic impairment
  • 5. Mental retarded and non-cooperative patients
  • 6. Patients with advanced heart failure, EF \<30%
  • 7. Patients have massive bleeding in the perioperative period, need for massive transfusion
  • 8. Patients have acute pulmonary pathology
  • 9. Patients with anaphylaxis who developed a blood product reaction
  • 10. Patients who do not allow a tidal volume of 8ml / kg in a mechanical ventilator

About Bakirkoy Dr. Sadi Konuk Research And Training Hospital

Bakirkoy Dr. Sadi Konuk Research and Training Hospital is a leading healthcare institution dedicated to advancing medical research and education. Located in Istanbul, Turkey, the hospital combines clinical excellence with a robust research framework, focusing on innovative treatment methodologies and patient care. As a prominent clinical trial sponsor, it fosters collaboration among multidisciplinary teams to facilitate groundbreaking studies that enhance medical knowledge and improve health outcomes. The institution is committed to adhering to the highest ethical standards and regulatory guidelines, ensuring the integrity and reliability of its research initiatives.

Locations

Istanbul, , Turkey

Patients applied

0 patients applied

Trial Officials

güneş özlem yildiz

Principal Investigator

bakırköy Dr. Sadi Konuk Education hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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