The Impact of Abdominal Wall Closure Technique on Incidence of Incisional Hernia in Kidney Transplantation

Launched by MANCHESTER UNIVERSITY NHS FOUNDATION TRUST · May 21, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how different techniques for closing the abdominal wall after kidney transplant surgery might affect the risk of developing incisional hernias, which are bulges that can occur at the site of the surgical scar. These hernias can lead to serious complications, including problems with the transplanted kidney, and they can also be uncomfortable or unsightly for patients. The researchers are looking at whether using smaller, more numerous stitches to close the wound can help reduce the chances of hernias forming compared to traditional methods. They will also collect blood and tissue samples from both kidney donors and recipients to better understand the biological factors that might increase the risk of hernia formation.

To be eligible for this trial, participants should be between 18 and 70 years old, be experiencing end-stage kidney failure, and be undergoing their first or second kidney transplant. They should also be able to understand English well enough to give consent and have a body mass index (BMI) of less than 35. The trial is currently recruiting participants, and those who join can expect to be monitored for any early complications after surgery and the rate of hernia development later on. This study aims to improve recovery outcomes for kidney transplant patients by testing a potentially better way to close surgical wounds.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • End-stage renal failure patients
• • Aged 18-70yrs
• • First transplants or second transplants
• • Ability to adequately understand English and consent for study
• • BMI\<35 kg/m2)
• • Living donor nephrectomy patients Exclusion Criteria
• • Outside age range,
• • Previous transplants which have left a scar in the ilia fossa