Individual Placement and Support and/or Cognitive Remediation Therapy Added to TAU in Patients With Early Schizophrenia

Launched by PAKISTAN INSTITUTE OF LIVING AND LEARNING · Jun 4, 2019

Keywords

ClinConnect Summary

This clinical trial is looking to explore new ways to help young adults with early signs of schizophrenia and related disorders. The researchers want to see if adding two specific therapies—Individual Placement and Support (IPS), which helps people find jobs and improve their work skills, and Cognitive Remediation Therapy (CRT), which focuses on improving thinking and memory skills—can be helpful when combined with the usual medication and support these patients receive. The goal is to find out if these additional therapies are practical and acceptable for patients who are just starting to experience these symptoms.

To be part of this study, participants need to be between 18 and 35 years old and have a confirmed diagnosis of schizophrenia or similar conditions. They should also have been stable on their medication for at least four weeks and be in touch with mental health services. Importantly, they should be within five years of their diagnosis and able to understand what it means to take part in the trial. During the study, participants can expect to receive support and therapies designed to help them manage their symptoms and improve their quality of life.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Male/Female patients aged between 18-35 years.
• • 2. Diagnosis of schizophrenia confirmed by SCID meeting DSM-V criteria for schizophrenia, schizophreniform or schizoaffective psychosis.
• • 3. Stable on medication for the past four weeks.
• • 4. In contact with mental health services
• • 5. Within 5 years of diagnosis.
• • 6. Able to demonstrate the capacity to provide informed consent to take part in this feasibility trial, as assessed by their own clinician.
• Exclusion Criteria:
• • 1. Active DSM-V substance abuse (except nicotine or caffeine) or dependence within the last three months
• • 2. Relevant CNS or other medical disorders
• • 3. Diagnosis of Learning Disability.