Characteristics and Inflammatory Markers in Children with Eosinophilic Esophagitis (EoE)

Launched by UNIVERSITY OF CALIFORNIA, SAN DIEGO · Jun 7, 2019

Keywords

ClinConnect Summary

This clinical trial is studying a condition called eosinophilic esophagitis (EoE) in children. EoE is an allergic reaction that affects the esophagus, which is the tube that carries food from the mouth to the stomach. The trial aims to understand the natural history of this condition and identify certain markers of inflammation that may be present in affected children. By gathering information and samples, researchers hope to learn more about how EoE develops and how it can be better treated.

To participate, children must already have a diagnosis of EoE and experience symptoms like difficulty swallowing, vomiting, or stomach pain. They may also have problems like food getting stuck in their throat or narrowing of the esophagus. There are no specific exclusions for this trial, making it more accessible for families. If eligible, participants will contribute to important research that could improve understanding and management of EoE, and they can expect to provide health information and samples during the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Have a known EoE diagnosis
• • Complain of dysphagia, vomiting, or abdominal pain, especially if recalcitrant to acid blocking therapy (but does not have to be recalcitrant to acid blocking medications)
• • Present with food impaction
• • Present with esophageal stricture
• • Have characteristic endoscopic findings of EoE of pallor, linear furrows, lichenification, white plaques, or concentric rings
• Exclusion Criteria:
• • None