Neural Control of Kidney Blood Flow During Exercise in African American Adults

Launched by UNIVERSITY OF MASSACHUSETTS, BOSTON · Jun 6, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how exercise affects blood flow to the kidneys in African American adults. Researchers want to understand if the body's response to exercise is different in this group compared to White adults, particularly focusing on the sympathetic nervous system, which is responsible for our fight-or-flight reactions. They believe that during exercise, African American adults may experience stronger kidney blood vessel constriction, which could lead to long-term health issues such as heart and kidney disease. By observing how the kidneys respond during exercise and other stress tests, the study aims to uncover important information that could help reduce the risk of these diseases in the future.

To participate in this trial, individuals must be healthy, self-identifying as either African American or White, and born in the United States. They should be physically active for at least 20 minutes several times a week but should not be training for competitions. Participants will undergo tests that measure blood flow and blood pressure while they exercise and during other stress-inducing activities. It’s important to note that individuals with certain health conditions, like high blood pressure or diabetes, or those who are pregnant, cannot participate. This study is a great opportunity for eligible individuals to contribute to research that could benefit their community's health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Self-report as either African American or White racial identity
• • Born in United States
• • Both biological parents identify as same racial identity as participant
• • Recreationally active (participating in physical activity for at least 20 minutes per day, at least three times per week, but not training for competitive events)
• • Fluent in English
• Exclusion Criteria:
• • Hispanic or Latino
• • Females who are pregnant or lactating
• • Cardiovascular or renal disease
• • Hypertension (blood pressure of more than or equal to 130/80 mmHg)
• • Diabetes
• • Obesity (body mass index of more than or equal to 30 kg/m2)
• • Smoker/Tobacco user
• • Acute medical conditions
• • Taking prescribed cardiovascular, antihypertensive, or renal medications