Management of Antiplatelet Regimen During Surgical Procedures

Launched by BAYLOR RESEARCH INSTITUTE · Jun 6, 2019

Keywords

ClinConnect Summary

The MARS registry is a clinical trial designed to improve how doctors manage patients who have recently undergone a procedure to open blocked arteries (called percutaneous coronary intervention, or PCI) and are taking blood-thinning medications known as dual antiplatelet therapy (DAPT). The study aims to gather important information about the practices doctors currently use when these patients need to have non-cardiac surgery or cardiac surgery. This is crucial because there are risks of bleeding and heart complications during these procedures, and the trial will help identify the safest approaches to managing these risks.

To participate in the study, patients should be between 65-74 years old, have had a PCI in the last two years, and be currently taking DAPT or have a reason to take it. They must also be scheduled for surgery. Participants will be asked to provide information about their health, and their experiences during the surgery will be monitored. This research is a significant step toward understanding and improving care for a large number of patients who face these situations. It is particularly important as it could lead to future studies that will provide even more insights into the best ways to manage patients on DAPT during surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with PCI within the past 2 years who: a. Are currently on DAPT, OR b. Have a current indication for DAPT
• • Scheduled for NCS or CS.
• • Willing and able to provide an informed consent (if needed based on institutional IRB requirements).
• Exclusion Criteria:
• • Emergent (6 hours) surgery post-PCI on DAPT that precludes a thorough informed consent process.