MRI Assessment of Pulmonary Edema in Acute Heart Failure

Launched by UNIVERSITY OF ALBERTA · Jun 25, 2019

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to measure how much fluid is in the lungs of people with acute heart failure, a condition where the heart can't pump blood effectively. Researchers are using a special imaging technique called MRI (Magnetic Resonance Imaging) to see how lung fluid levels change during a patient's hospital stay. By understanding these changes, the study aims to find out if higher or lower levels of lung water can help predict a patient’s risk of returning to the hospital or facing serious complications.

To participate in this trial, you need to be at least 18 years old and receiving treatment for acute heart failure. This includes patients who are being given medications to help reduce lung fluid, like diuretics. If you’re interested, you’ll have an MRI scan to measure your lung water shortly after starting treatment. It's important to note that certain factors, like being too ill to safely move to the MRI scanner or having severe dementia, might prevent someone from taking part. This study is currently looking for participants, and it could help improve care for future patients with heart failure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 18 years of age or older and willing/able to provide informed consent
• • patients being treated for acute heart failure (including those patients with both reduced and preserved ejection fraction)
• • patients receiving medical therapy for pulmonary edema by current standard of care (including oral or IV diuretics)
• • patients identified within 48 hours of initiation of medical therapy for pulmonary edema, defined as the time of first diuretic (IV or PO) or escalation of existing diuretic therapy administered within the ED or hospital
• Exclusion Criteria:
• • contraindication to MRI
• • patient too critically ill/unstable as per the clinical care team for transport to MRI scanner within the required scanning window
• • moderate to severe dementia