Influence of Central Versus Peripheral Vestibular Stimulation in Patients With Peripheral Vestibular Disorders

Launched by CAIRO UNIVERSITY · Jul 3, 2019

Keywords

ClinConnect Summary

This clinical trial is looking at two different types of non-invasive brain stimulation to see how they can help people with certain balance problems caused by a condition called unilateral peripheral vestibular disorders. These disorders can make it hard for individuals to perform daily activities and may lead to feelings of dizziness or trouble with balance. The researchers want to compare the effects of repetitive transcranial magnetic stimulation (rTMS) and galvanic vestibular stimulation to find out which one might be more effective for these patients.

To participate in the trial, individuals should be between 30 and 60 years old and must have been diagnosed with a specific type of vestibular disorder. They should have experienced symptoms like vertigo (a spinning sensation) for at least three months and may feel unsteady or have a moderate risk of falling. Participants will be medically stable and have not found relief from other treatments. Those who meet these criteria can expect to receive one of the two types of stimulation during the study, and their balance and symptoms will be closely monitored throughout the trial.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Definite diagnosis with unilateral peripheral vestibular disorders from audiologist or neurologist.
• • 2. The patient's age will be ranged from thirty to sixty years old.
• • 3. Patients will experience at least two symptoms of common symptoms of peripheral vestibular disorders.
• • 4. Symptoms of vertigo and nystagmus lasting from seconds to one minute.
• • 5. Vertigo that arises from changes in head position related to gravity.
• • 6. Patients who experienced symptoms for more than three months (chronic patients)
• • 7. Patients were selected to be ambulant.
• • 8. Patients suffer from balance disturbance with low risk falling (41-56) and moderate risk falling ranges (21-40) according to berg balance scale.
• • 9. All patients were medically stable, controlled with medical drugs for at least three months and failed to medical treatment with no other physical, mental or cognitive disorders.
• Exclusion Criteria:
• • 1. Benign positional vertigo.
• • 2. Central vestibular disorders ( Ms, ataxia, migraine headache, posterior inferior cerebellar artery syndrome "PICA").
• • 3. Vertigo that arises from changes in head position not related to gravity; as vertigo of cervical origin or vascular origin ( Vertebro- basilar insufficiency "VBI").
• • 4. Previous surgery of the ear.
• • 5. Bilateral peripheral vestibular weakness, central vestibular weakness, mixed vestibular weakness, or acute vestibular weakness.
• • 6. Unstable health issues (cardiac dysfunction, end stage renal failure, unstable diabetes, uncontrolled hypertension \>190/110...).
• • 7. Pacemaker or other implanted electrically sensitive device.
• • 8. Significant orthopedic or chronic pain syndrome (e.g any condition that wouldn't permit to completion of any of the tests).
• • 9. Major cognitive dysfunction. neurodegenerative disease or major psychiatric condition ( Alzheimer's disease , depression....).
• • 10. Chronic use of medications that could influence motor or sensory excitability (e.g AEDs, antipsychotic).
• • 11. Alcohol abuse.
• • 12. Epilepsy.