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Search / Trial NCT04017884

Evaluation of Remin Pro Forte Versus Remin Pro on Treatment of White Spot Lesions Post Orthodontic Treatment

Launched by CAIRO UNIVERSITY · Jul 11, 2019

Trial Information

Current as of August 11, 2025

Unknown status

Keywords

Remineralization Caries Regression Color Improvement

ClinConnect Summary

Recently, a remineralizing water based cream containing Hydroxyapatite, Fluoride and Xylitol (Remin pro) has been introduced. It has been claimed that hydroxyapatite fills eroded enamel, fluoride seals dentinal tubules and xylitol acts as an antibacterial agents. This product has been assumed to be suitable for management of dentinal hypersensitivity, prevention of enamel demineralization and promoting remineralization of enamel subsurface lesions. There are few studies regarding the effect of calcium phosphate and hydroxyapatite-based agents on remineralization and optical appearance of Wh...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 1. No systemic disease.
  • 2. Has completed fixed orthodontic treatment, brackets debonded.
  • 3. Has at least two teeth with white spot lesion.
  • 4. Has received conventional periodontal therapy after orthodontic treatment.
  • 5. Between the ages of 12 and 25 years of age.
  • Exclusion Criteria:
  • 1. Presence of enamel hypoplasia or dental fluorosis.
  • 2. Presence of tetracycline pigmentation.
  • 3. Periodontal pocketing of 3mm or greater.
  • 4. Taking antibiotics.
  • 5. Presence of carious cavities.
  • 6. Allergy to fluoride gel / varnish being used in study.
  • 7. Subjects who had evidence of reduced salivary flow or significant tooth wear

About Cairo University

Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.

Locations

Patients applied

0 patients applied

Trial Officials

mennatallah aboulnaga, MD

Principal Investigator

Cairo University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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