ECMO for Critically Ill Patients With Respiratory Failure and/or Circulatory Failure

Launched by MAHIDOL UNIVERSITY · Jul 22, 2019

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called ECMO, which stands for extracorporeal membrane oxygenation. ECMO is a method that helps support patients with severe breathing problems, specifically those suffering from acute respiratory distress syndrome (ARDS) and low oxygen levels that don’t improve with standard treatments. The goal of the study is to see how well ECMO works in hospitals that have less experience with this treatment, compared to traditional care methods.

To be eligible for this trial, participants must be diagnosed with ARDS and have very low oxygen levels that have not improved despite receiving the best available care, including mechanical ventilation. Patients should be between the ages of 65 and 74 and must have had their low oxygen levels for at least two hours. Those who are terminally ill or have certain serious health conditions, such as metastatic cancer, are not eligible. If you or a family member qualify, you can expect to be closely monitored and receive either ECMO or standard care, with the goal of improving health outcomes during a critical illness.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosed ARDS according to Berlin criteria
• • Refractory hypoxemia: PaO2/FiO2 \<100 with FiO2 \>90% despite optimal mechanical ventilator support and paralytic agent infusion
• • Hypoxemia persist for at least 2 hours
• Exclusion Criteria:
• • Terminally ill patient
• • Patient who sign for do not resuscitation
• • Metastatic malignancy