ClinConnect ClinConnect Logo
Search / Trial NCT04033224

Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure

Launched by CAREGGI HOSPITAL · Jul 25, 2019

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is looking at how extracorporeal blood purification therapies (EBPT) can help critically ill patients, particularly those dealing with severe conditions like acute kidney injury (AKI) or multiple organ failure. These therapies involve cleaning blood outside the body to improve health outcomes. The researchers want to see if certain groups of patients benefit more from these treatments, especially in terms of their chances of surviving after 28 days in the hospital.

To be eligible for this study, patients must be critically ill and receiving care in an intensive care unit (ICU). They should be undergoing specific EBPT methods to help with their kidney function or to reduce harmful substances in the blood. However, patients who are only receiving certain specialized treatments will not be included. If chosen to participate, patients and their families can expect close monitoring and to contribute to valuable research that may improve care for future patients in similar situations.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • critically ill patients in the ICU
  • * one of this EPB therapy:
  • CRRT/IHD/Hybrid therapies for support//replacement renal function
  • immunomodulation achieved by "high cut-off membranes", "endotoxins and/or cytokines adsorbent membranes" or by high-volume hemofiltration
  • Exclusion Criteria:
  • patients treated only by Cytosorb® and/or Toraymyxin® therapies

About Careggi Hospital

Careggi Hospital, located in Florence, Italy, is a leading academic medical center renowned for its commitment to advancing healthcare through innovative clinical research and trials. As a prominent sponsor of clinical studies, Careggi Hospital integrates cutting-edge medical practices with rigorous scientific methodology to enhance patient care and outcomes. The institution is dedicated to fostering collaborations among healthcare professionals, researchers, and academic institutions, ensuring that its trials adhere to the highest ethical and regulatory standards. With a focus on patient safety and evidence-based medicine, Careggi Hospital plays a pivotal role in translating research findings into effective therapies and treatments for a diverse range of medical conditions.

Locations

Pavia, , Italy

Brindisi, , Italy

Vicenza, , Italy

Torino, , Italy

San Donato Milanese, Milano, Italy

Florence, , Italy

Rozzano, Milano, Italy

Roma, , Italy

Florence, , Italy

Florence, Other, Italy

Empoli, Firenze, Italy

Lido Di Camaiore, Lucca, Italy

Monza, Monza Brianza, Italy

Pistoia, , Italy

Prato, , Italy

Reggio Calabria, , Italy

Roma, , Italy

Patients applied

0 patients applied

Trial Officials

Gianluca Villa, MD

Principal Investigator

University of Florence, Florence, Italy

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

Similar Trials