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Search / Trial NCT04034433

Exercise Program for Arteriovenous Fistula Maturation

Launched by HOSPICES CIVILS DE LYON · Jul 25, 2019

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Arteriovenous Fistula Diameter Handgrip Program Exercise Maturation

ClinConnect Summary

This clinical trial is studying whether a specific exercise program, called handgrip training, can help improve the size of an arteriovenous fistula (AVF) in patients with chronic kidney disease (CKD) who are preparing for hemodialysis. An AVF is a connection made between an artery and a vein to provide better access for dialysis treatment. Sometimes, these fistulas don’t work well, often because the vein is too small. The researchers want to see if doing handgrip exercises before and after the AVF surgery can help make the fistula bigger and more effective.

To participate in this study, you must be over 18 years old, have CKD with a specific level of kidney function (an eGFR of less than 30), and plan to undergo hemodialysis. You would need to be able to follow up with the University Hospital of Lyon Sud. However, if you have certain health issues that would prevent you from having an AVF or from doing the exercises, or if you’re involved in other clinical studies, you may not be eligible. If you join the trial, you can expect to engage in a handgrip exercise program alongside standard care, and the goal is to see if this training improves your AVF's success and overall treatment experience.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients older than 18 years
  • with chronic kidney disease (Estimated Glomerular Filtration Rate (eGFR) \<30 milliLiter/minute (mL/min))
  • with follow-up at the University Hospital of Lyon Sud
  • who choose hemodialysis as renal replacement therapy
  • Exclusion Criteria:
  • contraindication for arteriovenous fistula (AVF) surgery
  • refusing AVF creation
  • prior vascular access
  • antecedent of IV substance abuse
  • active cancer
  • inability to perform handgrip exercise
  • physical or mental disability limiting follow-up possibility
  • inclusion in an other interventional study
  • no social welfare

About Hospices Civils De Lyon

Hospices Civils de Lyon (HCL) is a leading public health institution in France, dedicated to providing high-quality healthcare and advancing medical research. With a rich history dating back to the 18th century, HCL encompasses multiple hospitals and offers a diverse range of services across various medical specialties. The institution is committed to fostering innovative clinical trials that aim to enhance patient care and improve therapeutic outcomes. By collaborating with academic and industry partners, HCL plays a pivotal role in the development of new treatments and the advancement of medical knowledge, ensuring that research efforts are aligned with the highest ethical standards and patient safety protocols.

Locations

Pierre Bénite, , France

Patients applied

0 patients applied

Trial Officials

Abbas DEEB, PhD

Principal Investigator

Hospices Civils de Lyon

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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