129Xe MRI in Pediatric Population With BPD

Launched by XEMED LLC · Jul 24, 2019

Keywords

ClinConnect Summary

This clinical trial, titled "129Xe MRI in Pediatric Population With BPD," is studying a new imaging technique called hyperpolarized gas MRI to better understand the lungs of infants with bronchopulmonary dysplasia (BPD). BPD is a serious lung condition that affects premature babies. The researchers believe that this MRI method can provide important information about the lungs that traditional imaging techniques, like CT scans, can't. This is particularly valuable because MRI uses no radiation, making it safer for young children.

To participate in this study, infants must be admitted to the Neonatal Intensive Care Unit (NICU) at the Children's Hospital of Philadelphia and have been diagnosed with BPD. They should also be on a ventilator and receiving sedation as part of their regular care. The trial is not yet recruiting participants, but if eligible, families can expect a thorough evaluation of their baby's lung function using this innovative MRI technique. It's important to note that only babies who are stable enough to be safely transported for the MRI will be included in the study.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Infants admitted to the NICU at the Children's Hospital of Philadelphia with bronchopulmonary dysplasia who are followed by the Chronic Lung Disease Program.
• • Subjects mechanically ventilated either via and endotracheal tube or via a tracheostomy.
• • Subjects already receiving sedation as part of clinical care.
• Exclusion Criteria:
• • - Infants whom the primary care team deems to be unstable for transport to MRI