RT-CGM in Young Adults at Risk of DKA

Launched by IMPERIAL COLLEGE LONDON · Jul 30, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how using a device called real-time continuous glucose monitoring (RT-CGM) might help young adults with type 1 diabetes who have difficulty controlling their blood sugar or have recently been hospitalized due to high blood sugar levels. The RT-CGM device provides constant updates on blood sugar levels, which may help people better manage their diabetes and potentially reduce hospital visits.

Young adults between 18 and 25 years old who have been managing their diabetes with insulin for at least a year, and who either have higher than recommended blood sugar levels or have had recent hospital admissions for diabetes-related issues, may be eligible to join. Participants should not have used RT-CGM regularly before, though using other types of glucose monitors in the past is allowed. If someone joins the study, they can expect to use the RT-CGM device to track their blood sugar closely, helping researchers see if this tool improves blood sugar control and reduces hospital stays. This pilot study will help guide larger future research to better support young adults with diabetes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Adolescents and young adults aged 18-25 years
• • Insulin-treated diabetes \>12 months (on multiple daily injections or insulin pump therapy)
• • HbA1c \> 75 mmol/mol (9%) or 1 or more DKA admissions in the last 12 months or 1 or more admissions with uncontrolled blood glucose levels in the last 12 months.
• • Naïve to RT-CGM - except for short periods for use for diagnosis or monitoring purposes.
• • Use of prior flash glucose monitoring is permittable
• Exclusion Criteria:
• • Chronic kidney disease eGFR \<30ml/min
• • Pregnant or planning pregnancy
• • Breastfeeding
• • Have active malignancy or under investigation for malignancy
• • Severe visual impairment
• • Reduced manual dexterity
• • Unable to participate due to other factors, as assessed by the Chief Investigator