Vicryl Rapide Versus Nonabsorbable Suture

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Aug 12, 2019

Keywords

ClinConnect Summary

This clinical trial is studying two types of stitches used for closing wounds caused by accidents, specifically looking at Vicryl Rapide versus nonabsorbable sutures. The goal is to find out if Vicryl Rapide, which dissolves over time, is just as effective as the traditional nonabsorbable stitches in terms of how well the wound looks three months after it has been stitched. The study will take place in the emergency department at Community Regional Medical Center.

To be eligible for the trial, participants must be at least 18 years old and have a single laceration on their trunk or extremities that is longer than 2 centimeters and needs to be closed with simple stitches. People with certain conditions, like high-risk infections or complicated wounds, won't be able to participate. If you join the study, you can expect to receive either type of suture for your wound and will be asked to return for a follow-up appointment in three months to assess how well the wound has healed. This trial is currently recruiting participants, and both men and women can take part.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient 18-years or older
• • single laceration on trunk or extremity requiring suture closure
• • laceration length \> 2-cm
• • wound to be closed with simple interrupted sutures
• Exclusion Criteria:
• • High infection potential
• * Must have one of the following:
• • puncture wound
• • -highly contaminated
• • devitalized tissue requiring sharp debridement
• • -bite wounds
• • -\> 24-hours-old
• • Low likelihood of good cosmesis
• * Must have one of the following:
• • -dehisced wound from previous wound closure
• • -wound
• • -crush wound
• • -soft tissue deficit limiting complete apposition of wound edges
• • -significant overlying macerated/abraded tissue
• • Underlying tendon or cartilage involvement
• • -Wound greater than 10 cm in length
• • Significant wound healing problems
• * Must have one of the following:
• • keloid formers
• • chronic steroid use
• • other: ______________________ -Inability to give written consent
• * Must have one of the following:
• • non-English or non-Spanish speaker
• • altered mental status
• • incarcerated patient
• • No telephone number or unlikely to return for 3-month follow-up
• * Must have one of the following:
• • homeless
• • psychiatric patient,
• • nursing home patient,
• • other: ______________________
• • More than one laceration needing suture repair on trunk or extremity (i.e. appropriate to proceed if second laceration is to face/neck)