Neurophysiological, Behavioral, and Cognitive Networks in Movement Disorders

Launched by UNIVERSITY OF ALABAMA AT BIRMINGHAM · Aug 15, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how the brain works in people with movement disorders like Parkinson's disease and essential tremor. These disorders not only affect movement but can also lead to other issues such as depression, trouble with memory, and difficulty in focusing. The researchers want to understand the brain activity related to both the movement and non-movement symptoms by recording brain activity during routine deep brain stimulation surgery, which is a common treatment for these conditions.

To join the study, participants need to be at least 18 years old and eligible for deep brain stimulation surgery based on a team evaluation. They should have a confirmed diagnosis of Parkinson's disease or essential tremor and be willing to take part in the study activities. Participants can expect to help researchers learn more about how these conditions affect the brain, which could lead to better treatments in the future. It's important to know that those who cannot give informed consent or have other health issues that prevent them from being surgical candidates will not be able to participate.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Eligible for DBS surgery based on multi-disciplinary consensus review
• • Have a diagnosis of Parkinson's disease or Essential Tremor
• • A minimum of 18 years of age
• • Willingness to participate in the paradigms described in the protocol
• Exclusion Criteria:
• • Inability to provide full and informed consent
• • Are not surgical candidates due to co-morbid conditions or pregnancy
• • Have not undergone an adequate trial of conservative medical management
• • Have a clinical presentation for which DBS surgery is not indicated
• • Are not able to participate in study-related activities