Non-invasive Continuous Cardiac Output Monitoring in Preterm Infants Study

Launched by IMPERIAL COLLEGE HEALTHCARE NHS TRUST · Aug 20, 2019

Keywords

ClinConnect Summary

The Non-invasive Continuous Cardiac Output Monitoring in Preterm Infants Study is looking at how we can safely and effectively monitor the heart function in newborn babies, especially those born early (preterm). The researchers want to see if a non-invasive method—meaning it doesn’t involve needles or surgery—can continuously measure the amount of blood the heart pumps out. They will also examine how this measurement changes when infants receive extra fluids or medications that help the heart work better.

To participate in this study, infants must be healthy term babies in the hospital within their first 72 hours or preterm babies admitted to the neonatal unit. Parents will need to give written consent for their babies to be part of the study. Unfortunately, babies with serious birth defects or those who are older than 12 hours, as well as those with very delicate skin, cannot participate. If enrolled, families can expect regular monitoring of their baby’s heart function without any invasive procedures, helping doctors better understand how to care for these vulnerable infants.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Healthy term infants in postnatal ward (within the first 72 hours of age)
• • Term and Preterm infants (including those with FGR) admitted to the neonatal unit
• • Written informed parental consent (prospective for postnatal ward and retrospective for babies admitted to the neonatal units)
• Exclusion Criteria:
• • Antenatal or postnatal diagnosis of severe congenital anomaly
• • Infants with no realistic chance of survival
• • Infants who are \>12 hours of age
• • Infants with fragile skin not permitting skin probe placement