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Search / Trial NCT04082130

Xenogenic Collagen Matrix and Subepithelial Connective Tissue Graft in the Treatment of Gingival Recession

Launched by DAMASCUS UNIVERSITY · Sep 5, 2019

Trial Information

Current as of May 29, 2025

Completed

Keywords

Xenogenic Collagen Matrix (Xcm). Subepithelial Connective Tissue Graft (Scgt). Coronally Advanced Flap (Caf). Root Coverage.

ClinConnect Summary

The aim of this study is to clinically compare between the subepithelial connective tissue graft (SCTG) plus coronally advanced flap (CAF) which is defined as the golden standard for the treatment of gingival recessions and Xenogenic collagen matrix (XCM) plus coronally advanced flap (CAF) to treat class I Miller gingival recession. CAF elevation will be done as it described by (De Sanctis \& Zucchelli 2007) with modifications in the the control group.The flap will be partially elevated in the (SCTG+CAF) group while it will be a split-full-split thickness flap in the (XCM+CAF) group, and fi...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Good general health.
  • No contraindications for periodontal surgery.
  • Presence of one localized gingival recession in each side of the maxilla and/or mandible, All recessions will be Class I defects (Miller 1985).
  • The cemento-enamel junction (CEJ) is visible in the defective teeth.
  • All patients demonstrating good plaque control.
  • No previous periodontal surgery in the targeted area.
  • Exclusion Criteria:
  • Smokers.
  • pregnant or nursing patients.
  • history of malignancy, radiotherapy, or chemotherapy.
  • Patients taking medications that affect mucosal healing.
  • Patients with allergy to collagen.
  • Previous participation in a clinical trial.
  • Type-1 diabetes patients.
  • Patient who have diseases that affect connective tissue metabolism.

About Damascus University

Damascus University, a prestigious institution located in Syria, is committed to advancing medical research and healthcare innovation through its clinical trial initiatives. With a focus on fostering collaboration between academia and clinical practice, the university aims to enhance the understanding of various medical conditions and improve patient outcomes. By leveraging its extensive network of researchers, healthcare professionals, and state-of-the-art facilities, Damascus University strives to contribute to the global body of knowledge in the medical field and support the development of effective therapeutic interventions.

Locations

Damascus, , Syrian Arab Republic

Patients applied

0 patients applied

Trial Officials

Noor Alhuda Ewaz Ali, DDS

Principal Investigator

MSc student in Periodontics, University of Damascus Dental School

Suleiman Dayoub, DDS MSc PhD

Study Chair

Professor of Periodontics, University of Damascus Dental School

Mohammad Alharissy, DDS MSc PhD

Study Director

Assistant Professor of Periodontics, Academic Staff Member At Wadi International University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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