Prostate Cancer Patients Treated With Alternative Radiation Oncology Strategies

Launched by UNIVERSITY HOSPITAL HEIDELBERG · Sep 9, 2019

Keywords

ClinConnect Summary

The PAROS study is a clinical trial that is investigating a new approach to treating prostate cancer using a type of radiation therapy called proton therapy. This study aims to see if using protons can improve patients' quality of life by reducing side effects, particularly those affecting the rectum, after surgery. The trial will also check if this method is just as effective as traditional radiation therapy in treating cancer after surgery.

To participate in this trial, men aged 18 and older need to have a confirmed diagnosis of prostate cancer and require radiation treatment after having their prostate removed. However, individuals who have had certain previous treatments, such as hormone therapy or radiation, or those with advanced cancer, will not be eligible. If you qualify and decide to join, you can expect to receive radiation therapy as part of the study, and you will be closely monitored throughout the process to evaluate your health and any side effects you may experience. This trial is an important step in finding better treatment options for prostate cancer patients.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • histology-proven prostate cancer with Gleason Score and PSA-value;
• • indication for prostate bed irradiation (adjuvant/ salvage) after prostatectomy;
• • Karnofsky-Index ≥ 70%
• • age ≥ 18 years
• Exclusion Criteria:
• • androgen deprivation therapy
• • lymphatic spread
• • macroscopic tumor/ R2
• • stage IV (M1)
• • previous irradiation