Antibiotic-induced Disruption of the Microbiota

Launched by UNIVERSITY OF FRIBOURG · Sep 12, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how antibiotics affect the bacteria in our bodies, specifically in healthy infants. Researchers want to understand how antibiotics given during birth and early life change the bacteria found in breast milk and in the baby's mouth and gut. They are looking to see if these changes are only temporary or if they last for a long time.

Healthy infants who are born at full term (more than 37 weeks) may be eligible to participate in this study. However, infants with certain health conditions or whose mothers had specific infections or took antibiotics during pregnancy cannot join. Participants can expect to provide samples that will help researchers learn more about the relationship between antibiotics and changes in their microbiota. This study is important because it could help us understand how to better support the health of infants after they receive antibiotics.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • healthy infants
• • term infants (\> 37 weeks of gestation)
• Exclusion Criteria:
• • maternal HIV infection
• • maternal hepatitis B or C infection
• • antibiotics in the third trimester of pregnancy
• • intake of probiotics during pregnancy
• • infants with the low birth weight \<2500 g
• • infants with congenital abnormality