Study of Direct Brain Recording and Stimulation for Memory Enhancement
Launched by NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE (NINDS) · Sep 18, 2019
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Objective
The primary objectives of this study are (1) to identify biomarkers of successful memory encoding and retrieval, and (2) to identify brain regions that can be stimulated to affect memory performance. The secondary objective is to identify biomarkers that can be used to predict cognitive impairment following resection surgery.
Study Population
One hundred (100) adult subjects with epilepsy who are enrolled in 11-N-0051 Epilepsy Surgery protocol.
Study Design
We plan to enroll individuals with drug resistant epilepsy who are enrolled in a separate protocol, 11-N-0051 Epilepsy S...
Gender
ALL
Eligibility criteria
- * INCLUSION CRITERIA:
- To be eligible for entry into the study, candidates must meet all the following criteria:
- • Be enrolled in 11-N-0051 Epilepsy Surgery.
- • Able to give informed consent.
- • Age greater than or equal to 18 years and less than or equal to 65 years
- EXCLUSION CRITERIA:
- Candidates will be excluded if they:
- • -Have any disability that would limit their ability to perform study tasks that examine memory function.
About National Institute Of Neurological Disorders And Stroke (Ninds)
The National Institute of Neurological Disorders and Stroke (NINDS) is a leading component of the National Institutes of Health (NIH), dedicated to advancing our understanding of the brain and nervous system through innovative research. NINDS sponsors and conducts clinical trials aimed at developing effective treatments and improving patient outcomes for a wide range of neurological disorders, including stroke, epilepsy, multiple sclerosis, and neurodegenerative diseases. By fostering collaboration among researchers, healthcare providers, and patient communities, NINDS plays a pivotal role in transforming scientific discoveries into clinical applications, ultimately enhancing the quality of life for individuals affected by neurological conditions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bethesda, Maryland, United States
Bethesda, Maryland, United States
Patients applied
Trial Officials
Kareem A Zaghloul, M.D.
Principal Investigator
National Institute of Neurological Disorders and Stroke (NINDS)
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials