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Search / Trial NCT04099225

Multiple Breath Washout (MBW) Using Sulfur Hexafluoride Reference Values and Influence of Anthropometric Parameters

Launched by UNIVERSITÄTSMEDIZIN MANNHEIM · Sep 19, 2019

Trial Information

Current as of September 26, 2025

Completed

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • non-smoker
  • no history of pulmonary disease
  • absence of dyspnoea, cough, thoracic pain
  • no self-reported smoking history
  • normal lung function testing
  • normal shape of flow-volume curve
  • normal shape of flow-pressure curve
  • FEV1/FVC \>70% (forced expiratory volume in 1 second / forced vital capacity)
  • TLC \> 80% of predicted (total lung capacity)
  • TLCO/VA \> 80% of predicted (transfer factor corrected for ventilated alveolar volume)
  • R5 \< 150% of predicted (resistance at 5Hz, impulse oscillometry)
  • smoker
  • - as above, but with self-reported smoking history \>10 pack years
  • Exclusion Criteria:
  • unwilling or unable to give informed consent
  • history of any respiratory disease

About Universitätsmedizin Mannheim

Universitätsmedizin Mannheim is a leading academic medical center affiliated with Heidelberg University, dedicated to advancing healthcare through innovative research and clinical trials. With a strong emphasis on translational medicine, the institution integrates cutting-edge scientific discovery with patient care, fostering collaboration among multidisciplinary teams. Its state-of-the-art facilities and commitment to ethical research practices position Universitätsmedizin Mannheim as a pivotal contributor to the development of new therapies and medical technologies, ultimately enhancing patient outcomes and contributing to the global body of medical knowledge.

Locations

Patients applied

0 patients applied

Trial Officials

Frederik Trinkmann, MD

Principal Investigator

University Medical Center Mannheim

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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