NIRS in Congenital Heart Defects - Correlation With Echocardiography

Launched by MCGILL UNIVERSITY HEALTH CENTRE/RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE · Sep 25, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how well a special device called near infrared spectroscopy (NIRS) can help monitor blood flow and oxygen levels in newborns with congenital heart defects (CHD). These heart defects can affect how blood moves throughout the body, especially in the critical first week of life. The researchers will compare the results from NIRS with traditional heart imaging tests called echocardiograms to see how well they match up. This could help doctors better understand how to care for these newborns.

To participate in the trial, babies must be diagnosed with specific congenital heart defects, such as Tetralogy of Fallot or Atrioventricular Canal defects, and be admitted to the neonatal intensive care unit (NICU) at Montreal Children's Hospital. Babies who are born prematurely (before 34 weeks) or whose parents do not give consent will not be eligible. Throughout the study, parents will be informed about what to expect and can withdraw their consent at any time. This research aims to improve care for newborns with heart conditions and ensure they receive the best possible treatment.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A prospective study will be conducted of all newborns with tetralogy of fallot, trucus arteriosus, D-transposition of great arteries, PS, AS, coarctation of the aorta, DILV, AVC, DORV, HLHS, TA and PAIVS consecutively admitted at our institution (Montreal Children's Hospital) neonatal intensive care unit (NICU) from January 2018 to January 2020. Patients with CHD will be compared to a control population of term infants admitted and monitored in the NICU with antenatal suspicion of coarctation, ruled-out postnatally.
• Exclusion Criteria:
• • Patients will be excluded if premature less than 34 weeks of estimated gestational age (GA) at birth or if parents do not consent. Parental consent can be withdrawn at any time during the study.