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Search / Trial NCT04114786

3D Printed Mask for GBM and Brain Mets

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Oct 1, 2019

Trial Information

Current as of June 17, 2025

Completed

Keywords

Radiation Brain Cancer Glioblastoma 3 D Printed Mask

ClinConnect Summary

All patients referred for radiotherapy have had a previous diagnostic imaging study (CT-scan or more commonly MRI) showing the disease at the central nervous system (CNS). Moreover, after surgical biopsy or resection, many Centers perform repeated post-operative imaging. Despite all prior imaging, when radiotherapy treatment is decided, all patients undergo another imaging study (CT simulation \[CT-sim\]) in which patient's head is placed in a reproducible position, and endure a moulding procedure to create a personalized plastic mask for securing the patient's head in a fixed position duri...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age \>18 years
  • Patient with high-grade glioma considered for external beam radiotherapy (15 fractions or more) with or without Temozolamide, or patients with brain metastases considered for fractionated LINAC-based external beam radiotherapy (5 fractions or more) as primary or adjuvant treatment.
  • No contraindications to MRI
  • No other medical conditions deemed by the PI to make patient ineligible for the study (i.e. claustrophobia, confusion, delirium).
  • Exclusion Criteria:
  • None

About University Health Network, Toronto

University Health Network (UHN), based in Toronto, is a leading academic health sciences center dedicated to advancing patient care through innovative research and education. As a prominent sponsor of clinical trials, UHN integrates cutting-edge scientific discoveries with clinical practice, facilitating the development of new therapies and treatment modalities. With a commitment to improving health outcomes, UHN collaborates with a diverse network of researchers, healthcare professionals, and industry partners, fostering an environment that prioritizes patient safety and ethical standards in clinical research. Through its extensive resources and expertise, UHN plays a pivotal role in transforming healthcare and enhancing the quality of life for patients both locally and globally.

Locations

Toronto, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Alejandro Berlin, <D

Principal Investigator

Princess Margaret

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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