Safety and Efficacy of Edoxaban in Thoracoscopic Ablation

Launched by SAMSUNG MEDICAL CENTER · Oct 8, 2019

Keywords

ClinConnect Summary

In Korea, 5% of patients older than 65 years and 10% of patients older than 80 have a history of atrial fibrillation (AF), which is often associated with sudden death and stroke. Medication and percutaneous radiofrequency catheter ablation are commonly used treatment modalities. Pharmacotherapy is primarily symptomatic treatment; moreover, the effect of conversion to a normal rhythm is minimal, and mainly aimed at stabilizing heart rate. Catheter ablation is associated with a high incidence of recurrence in chronic AF, and it is difficult to treat left atrial appendage, thereby preventing d...

Gender

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Eligibility criteria

• Inclusion Criteria:
• • 1. Patients aged 18 years or older (not exceed 80 years old).
• • 2. Elective thoracoscopic ablation.
• • 3. Presence of atrial fibrillation (paroxysmal, persistent, long-standing persistent).
• Exclusion Criteria:
• • 1. Chronic obstructive pulmonary disease (COPD).
• • 2. History of pulmonary tuberculosis.
• • 3. Other cardiac comorbidities including valvular disease, coronary artery disease.
• • 4. Congenital heart anomalies except for atrial septal defect.
• • 5. Known, clinically important anemia or thrombocytopenia.
• • 6. Pregnancy or lactation.
• • 7. Malignancy.
• • 8. Intracardiac mass or thrombus
• • 9. Life expectancy less than 1 year.