Impact of Adrenal IncidenTalomas and Possible Autonomous Cortisol Secretion on Cardiovascular and Metabolic Alterations

Launched by UNIVERSITY OF ROMA LA SAPIENZA · Oct 11, 2019

Keywords

ClinConnect Summary

This clinical trial is studying how certain growths on the adrenal glands, known as adrenal incidentalomas, may affect heart health and metabolism. The researchers believe that these growths can lead to changes in how your body processes sugar and fats, which might increase the risk of heart problems. They are also exploring whether removing these growths, in selected patients, can help improve these health issues, based on specific medical guidelines.

To be eligible for the trial, you should have an adrenal mass that was found by accident during imaging tests for another reason. However, if you have certain conditions like Cushing's syndrome or are taking medications that affect hormone levels, you won't be able to participate. If you join the trial, you can expect to undergo assessments to understand your health better, and if appropriate, you may have the option for surgery to remove the adrenal mass. This study is currently looking for participants aged between 65 and 74, and they welcome individuals of all genders.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Incidentally detected adrenal mass
• Exclusion Criteria:
• • Patients with overt Cushing's syndrome, pheochromocytoma, Conn syndrome, adrenocortical carcinoma, late-onset congenital adrenal hyperplasia, adrenal metastasis and adrenal hemorrhage
• • Patients taking medications influencing glucocorticoid production or metabolism
• • Patients with psychiatric diseases or alcohol abuse
• • Pregnancy