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Search / Trial NCT04129775

OTO-413 in Subjects With Speech-in-Noise Hearing Impairment

Launched by OTONOMY, INC. · Oct 14, 2019

Trial Information

Current as of May 21, 2025

Completed

Keywords

Hearing Loss Speech In Noise Synaptopathy Hearing Impairment Hidden Hearing Loss

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Subject has audiometrically-defined normal hearing or up to moderately severe hearing impairment.
  • Subject has self-reported difficulty hearing in noisy environments for at least 6 months prior to Screening.
  • Subject exhibited a speech-in-noise hearing deficit in at least one ear.
  • Exclusion Criteria:
  • Subject is pregnant or lactating.
  • Subject has the following hearing disorders or any other hearing disorders that may impact the efficacy assessments or safety of the subject in the opinion of the Investigator: Meniere's disease, congenital hearing loss, or genetic sensorineural hearing loss.
  • Subject has a cochlear implant or consistently uses a hearing aid.
  • Subject has worked at least 5 years as a professional musician or has had at least 15 years of formal musical training.
  • Subject self-reports bothersome, subjective tinnitus and is consistently aware of their tinnitus throughout much of the waking day.

About Otonomy, Inc.

Otonomy, Inc. is a biopharmaceutical company focused on developing innovative therapeutics for the treatment of ear disorders. With a commitment to advancing patient care, Otonomy leverages its proprietary drug delivery technologies to address unmet medical needs in conditions such as hearing loss and chronic ear diseases. The company's robust pipeline includes both clinical and preclinical programs aimed at providing effective and long-lasting treatment options. Otonomy is dedicated to improving the lives of patients through scientific excellence and a patient-centered approach to drug development.

Locations

Tampa, Florida, United States

Winston Salem, North Carolina, United States

Hollywood, Florida, United States

Salt Lake City, Utah, United States

Colorado Springs, Colorado, United States

Miami, Florida, United States

Louisville, Kentucky, United States

Norfolk, Virginia, United States

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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