Intraperitoneal Infusion of Analgesic for Postoperative Pain Management

Launched by YING LIU · Oct 16, 2019

Keywords

ClinConnect Summary

This clinical trial is studying a new way to help manage pain after a minimally invasive hysterectomy, which is a surgery to remove the uterus. The goal is to see if using a special pain relief method called intraperitoneal infusion—where a local anesthetic (a medicine that numbs pain) is delivered directly into the abdomen—can reduce postoperative pain and the need for narcotics (strong pain medicines). Some participants will receive the local anesthetic alone, while others will receive it combined with another pain relief medicine, and a control group will get a saline solution (a simple saltwater solution) to compare results.

If you’re a woman aged between 18 and 80 who is scheduled for a hysterectomy for a non-cancerous reason, such as fibroids or severe pelvic pain, you may be eligible to join this study. Participants will be recruited from hospitals and will have their surgeries performed by specially trained surgeons. During the trial, you can expect to receive treatment as part of the study and complete some questionnaires to help researchers understand your pain levels and recovery. It's important to note that if you have any allergies to the medications being studied or if there are concerns about cancer, you might not be able to participate. This trial aims to improve postoperative pain management and could lead to more effective treatments for future patients.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Hysterectomy planned for a benign gynecologic reason (no evidence of, or concern for, malignancy in the cervix, uterus, tubes or ovaries. Benign gynecologic reasons to have a hysterectomy include fibroids, abnormal uterine bleeding, endometriosis, and pelvic pain.)
• • Patient is scheduled to have surgery with a fellowship trained minimally invasive gynecologic surgeons at one of the study sites.
• • Patient is planned for a robotic assisted total laparoscopic hysterectomy (RA-TLH) or a total laparoscopic hysterectomy (TLH).
• • Patient is capable of informed consent.
• • Patient is capable of completing the questionnaires.
• Exclusion Criteria:
• • Concern for malignancy
• • The procedure is scheduled outside MIGS department.
• • Allergy to any study related medication (i.e. Ketorolac and Ropivacaine)
• • Patient is enrolled in another pain management study.