Rehabilitation Manometry Study
Launched by UNIVERSITY OF WISCONSIN, MADISON · Oct 15, 2019
Trial Information
Current as of July 26, 2025
Recruiting
Keywords
ClinConnect Summary
The Rehabilitation Manometry Study is researching how to better measure and improve swallowing difficulties, known as oropharyngeal dysphagia, which affects many adults. This condition makes it hard to swallow and can significantly impact a person's physical and emotional well-being. The study will use a special test called pharyngeal high-resolution manometry (pHRM) to observe how well people swallow and to see if certain treatments, like strengthening exercises or surgery to remove blockages, can help. Researchers will compare the results of participants with swallowing difficulties to healthy individuals to understand the effects of these treatments.
To participate, individuals must be diagnosed with dysphagia and have a treatment plan that focuses on improving swallowing strength or relieving blockages in the throat. They should also be willing to undergo swallowing assessments and sign consent forms. People without swallowing disorders can also join the study as a comparison group. Participants will undergo assessments at three different points during their treatment—before it starts, midway through, and after it’s completed—so the researchers can track changes and outcomes effectively. This study aims to provide valuable insights into how to better treat swallowing difficulties and help those affected.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Pathological Group
- * Must have dysphagia as diagnosed by a licensed and certified otolaryngologist, gastroenterologist, or speech-language pathologist AND must have a dysphagia treatment plan that includes one of the following primary goals:
- • Therapy to strengthen oropharyngeal musculature
- • Medical or surgical management to relieve an obstruction at the upper esophageal sphincter
- • Must agree to comply with swallowing assessment, including interview and manometry
- • Must sign the Informed Consent form approved by the Health Sciences Institutional Review Board of the University of Wisconsin
- • Normal Group
- • Having no swallowing disorders
- • Must agree to comply with swallowing assessment, including interview and manometry
- • Must sign the Informed Consent form approved by the Health Sciences Institutional Review Board of the University of Wisconsin.\\
- Exclusion Criteria:
- • Pathological Group
- • Therapeutic management plan already initiated prior to recruitment
- • Therapy goals including only improvement of swallowing coordination
- • Developmental disability, dementia, cognitive dysfunction, or difficulty comprehending instructions
- • Positive history of allergic response to topical anesthetic
- • Allergy to food relevant to study participation (e.g. lactose intolerance)
- • Normal Group
- • Known swallowing disorder
- • Developmental disability, dementia, cognitive dysfunction, or difficulty comprehending instructions
- • Positive history of allergic response to topical anesthetic
- • Allergy to food relevant to study participation (e.g. lactose intolerance)
About University Of Wisconsin, Madison
The University of Wisconsin-Madison is a leading research institution renowned for its commitment to advancing healthcare through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university leverages its extensive resources, including cutting-edge facilities and a diverse pool of expert researchers, to conduct rigorous studies that address critical health challenges. The institution's focus on translating research findings into practical applications fosters the development of new treatments and interventions, ultimately contributing to improved patient outcomes and public health initiatives. As a sponsor of clinical trials, the University of Wisconsin-Madison is dedicated to upholding the highest ethical standards and ensuring participant safety throughout the research process.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Madison, Wisconsin, United States
Patients applied
Trial Officials
Timothy McCulloch, MD, FACS
Principal Investigator
University of Wisconsin, Madison
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials