To Compare Ridge Preservation Technique Using Leukocyte Platelet Rich Fibrin (L-PRF) and Freeze-dried Bone Allograft (FDBA) Layered Technique vs L-PRF/FDBA and L-PRF Alone in Influencing Quantity and Quality of New Bone Formation in Grafted Extraction Sockets

Launched by UNIVERSITY OF ALABAMA AT BIRMINGHAM · Oct 17, 2019

Keywords

ClinConnect Summary

This study is a prospective, three-arm randomized trial that will evaluate and compare the bone healing following ridge preservation of extraction sockets using either L-PRF/FDBA layered technique or L-PRF/FDBA or L-PRF alone in a total of 30 patients (10 in each arm).

Qualifying participants and defects will be randomized following a computerized permutation block to receive either technique on day of surgery. Tooth extraction will be performed with a flapless minimally invasive technique, followed by socket grafting with a randomized graft.

The mineralized cortico-cancellous bone allogr...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • English speaking and able to read and understand English informed consent document
• • At least 18 years old.
• • Must be a patient at the UAB School of Dentistry
• • Patient is willing and able to comply with all steps of the study
• • Hopeless single-rooted tooth planned to be replaced with a dental implant and with healthy adjacent teeth not planned for extraction.
• Exclusion Criteria:
• • Patients with systemic pathologies or conditions contraindicating oral surgical procedures or adversely affecting wound healing
• • Pregnant women
• • Patient is a poor compliance risk (i.e., poor oral hygiene, history of alcohol or drug abuse)