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Search / Trial NCT04139616

Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following TAVR

Launched by CENTRE DE RECHERCHE DE L'INSTITUT UNIVERSITAIRE DE CARDIOLOGIE ET DE PNEUMOLOGIE DE QUEBEC · Oct 23, 2019

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Atrioventricular Block Complete Heart Block High Degree Atrioventricular Block Intraventricular Conduction Delay Left Bundle Branch Block Permanent Pacemaker Implantation Right Bundle Branch Block

ClinConnect Summary

This clinical trial is looking at how to best manage a condition called conduction disturbances, which can occur after a procedure known as Transcatheter Aortic Valve Replacement (TAVR). Conduction disturbances affect the heart's electrical signals and can lead to serious complications, including the need for a permanent pacemaker. The goal of this study is to test a specific treatment plan to see if it can help reduce the need for a pacemaker while keeping patients safe from life-threatening heart issues after they leave the hospital.

To be eligible for this trial, participants should be adults aged 65 to 74 who are scheduled to have TAVR due to aortic valve disease. It's important to note that those who have had a permanent pacemaker before or who cannot commit to following the study guidelines will not be included. If you join the trial, you can expect to receive careful monitoring and treatment according to the study's plan, which aims to improve heart health outcomes after TAVR. Your participation could help doctors understand the best ways to care for patients experiencing conduction disturbances in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • -Patients with aortic valve disease undergoing transcatheter aortic valve replacement
  • Exclusion Criteria:
  • Prior permanent pacemaker
  • Failure to provide signed informed consent for data collection
  • Impossibility for a follow-up
  • Unwillingness to follow the pre-specified strategy for the management of conduction disturbances

About Centre De Recherche De L'institut Universitaire De Cardiologie Et De Pneumologie De Quebec

The Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Québec (CRIUCQ) is a leading research institution dedicated to advancing knowledge and innovation in cardiovascular and pulmonary health. Affiliated with the Université Laval, CRIUCQ focuses on interdisciplinary clinical and translational research, aiming to improve patient outcomes through state-of-the-art methodologies and collaborative approaches. The center fosters a dynamic environment for researchers, clinicians, and healthcare professionals to explore cutting-edge treatments and interventions, contributing significantly to the global understanding of cardiopulmonary diseases. With a commitment to excellence, CRIUCQ plays a pivotal role in shaping the future of cardiovascular and respiratory medicine.

Locations

Quebec, , Canada

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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