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Search / Trial NCT04148859

Feto-Fetal Transfusion Syndrome in Multiple Pregnancies

Launched by TEL-AVIV SOURASKY MEDICAL CENTER · Oct 30, 2019

Trial Information

Current as of July 01, 2025

Recruiting

Keywords

Ttts Controlled Amnioreduction Amniotic Pressure

ClinConnect Summary

This clinical trial is studying a condition called Twin-to-Twin Transfusion Syndrome (TTTS), which can occur in pregnancies with identical twins. TTTS happens when one twin gets too much blood and the other gets too little, which can be risky for both babies. The trial is looking at a procedure called controlled amnioreduction (AR), where doctors carefully remove some of the fluid surrounding the babies to help balance their blood flow. They will measure the pressure of the fluid and the amount removed during the procedure, and also check the health of the babies over time.

To participate in this study, women need to be pregnant with twins that have been diagnosed with severe TTTS. However, those with other serious issues, like malformations or genetic problems in the twins, will not be included. Participants can expect to undergo the AR procedure between the 17th and 34th weeks of their pregnancy and will be monitored closely for the health of their babies. The study also aims to assess how the twins are doing as they grow, using questionnaires to evaluate their overall health and development. If you're considering joining this trial, it could provide valuable insights into managing TTTS and improving outcomes for twins.

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • Pregnancies with TTTS
  • Exclusion Criteria:
  • Pregnancies with malformations or genetic pathologies

About Tel Aviv Sourasky Medical Center

Tel Aviv Sourasky Medical Center, a leading academic medical institution in Israel, is renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a multidisciplinary approach, the center integrates cutting-edge medical technology and evidence-based practices to enhance patient care and outcomes. Its robust infrastructure supports a diverse range of clinical studies, fostering collaboration among healthcare professionals, researchers, and industry partners. The center's dedication to research excellence and patient safety positions it as a key player in the global clinical research landscape, driving advancements in medical knowledge and treatment options.

Locations

Tel Aviv, , Israel

Patients applied

0 patients applied

Trial Officials

Ariel J Jaffa, MD

Principal Investigator

Ultrasound Unit in Obstetrics and Gynecology, Lis Maternity Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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