Comprehensive Aneurysm Management Trial
Launched by CENTRE HOSPITALIER DE L'UNIVERSITÉ DE MONTRÉAL (CHUM) · Nov 5, 2019
Trial Information
Current as of August 26, 2025
Recruiting
Keywords
ClinConnect Summary
The Comprehensive Aneurysm Management Trial (CAM) is studying the best ways to manage unruptured intracranial aneurysms (UIAs), which are bulges in blood vessels in the brain that have not yet caused any symptoms. The trial aims to find out if patients do better in the long run when they receive active treatment (like surgery or endovascular methods) compared to simply monitoring their condition. It also looks at which treatment option might be better when both surgical and endovascular treatments are reasonable choices. The main goal is to see if treatment can reduce serious health issues or death over ten years.
If you are between the ages of 65 and 74 and have at least one documented intracranial aneurysm, you might be eligible to participate in this study. However, those who have had a brain hemorrhage recently or certain other conditions may not qualify. Participants will be followed for ten years to track their health outcomes, including any complications related to their aneurysm or treatment. This trial offers a chance to contribute to understanding how best to manage these conditions and improve patient care.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with at least one documented, intracranial subarachnoid aneurysm (cavernous aneurysms are excluded)
- Exclusion Criteria:
- • Patients with any intracranial hemorrhage, including SAH, within the previous 30 days
- • Patients with AVM-associated aneurysms
- • Patients unable to give informed consent
About Centre Hospitalier De L'université De Montréal (Chum)
The Centre Hospitalier de l'Université de Montréal (CHUM) is a leading academic health institution in Canada, dedicated to advancing patient care through innovative research and clinical excellence. As a prominent sponsor of clinical trials, CHUM is committed to leveraging its multidisciplinary expertise and state-of-the-art facilities to facilitate groundbreaking studies that enhance medical knowledge and improve health outcomes. Collaborating with a network of healthcare professionals and researchers, CHUM fosters a rigorous research environment that prioritizes patient safety, ethical standards, and scientific integrity, positioning itself at the forefront of medical advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Edmonton, Alberta, Canada
Montreal, Quebec, Canada
Tours, , France
Edmonton, Alberta, Canada
Montreal, Quebec, Canada
Bergamo, , Italy
Lecce, , Italy
Milan, , Italy
Patients applied
Trial Officials
Tim Darsaut, MD
Principal Investigator
Neurosurgeon University of Alberta Health
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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