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Search / Trial NCT04155606

Comprehensive Aneurysm Management Trial

Launched by CENTRE HOSPITALIER DE L'UNIVERSITÉ DE MONTRÉAL (CHUM) · Nov 5, 2019

Trial Information

Current as of August 26, 2025

Recruiting

Keywords

Unruptured Intracranial Aneurysm Endovascular Treatment Surgical Treatment Conservative Management

ClinConnect Summary

The Comprehensive Aneurysm Management Trial (CAM) is studying the best ways to manage unruptured intracranial aneurysms (UIAs), which are bulges in blood vessels in the brain that have not yet caused any symptoms. The trial aims to find out if patients do better in the long run when they receive active treatment (like surgery or endovascular methods) compared to simply monitoring their condition. It also looks at which treatment option might be better when both surgical and endovascular treatments are reasonable choices. The main goal is to see if treatment can reduce serious health issues or death over ten years.

If you are between the ages of 65 and 74 and have at least one documented intracranial aneurysm, you might be eligible to participate in this study. However, those who have had a brain hemorrhage recently or certain other conditions may not qualify. Participants will be followed for ten years to track their health outcomes, including any complications related to their aneurysm or treatment. This trial offers a chance to contribute to understanding how best to manage these conditions and improve patient care.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients with at least one documented, intracranial subarachnoid aneurysm (cavernous aneurysms are excluded)
  • Exclusion Criteria:
  • Patients with any intracranial hemorrhage, including SAH, within the previous 30 days
  • Patients with AVM-associated aneurysms
  • Patients unable to give informed consent

About Centre Hospitalier De L'université De Montréal (Chum)

The Centre Hospitalier de l'Université de Montréal (CHUM) is a leading academic health institution in Canada, dedicated to advancing patient care through innovative research and clinical excellence. As a prominent sponsor of clinical trials, CHUM is committed to leveraging its multidisciplinary expertise and state-of-the-art facilities to facilitate groundbreaking studies that enhance medical knowledge and improve health outcomes. Collaborating with a network of healthcare professionals and researchers, CHUM fosters a rigorous research environment that prioritizes patient safety, ethical standards, and scientific integrity, positioning itself at the forefront of medical advancements.

Locations

Edmonton, Alberta, Canada

Montreal, Quebec, Canada

Tours, , France

Edmonton, Alberta, Canada

Montreal, Quebec, Canada

Bergamo, , Italy

Lecce, , Italy

Milan, , Italy

Patients applied

0 patients applied

Trial Officials

Tim Darsaut, MD

Principal Investigator

Neurosurgeon University of Alberta Health

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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