Hyperinflation Respiratory Therapies in Cardiac Surgery Patients
Launched by UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER · Nov 14, 2019
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at different breathing treatments that can help patients recover better after heart surgery. Specifically, researchers want to find out which of three types of therapies—Intermittent Positive Pressure Breathing (IPPB), Intermittent Positive End Expiratory Pressure (EzPAP), and Metaneb—works best to expand the lungs and improve recovery. The study is currently recruiting participants who are 18 years or older and have recently undergone heart surgery, such as coronary artery bypass grafting or valve repair.
To be eligible, patients must be admitted to the Cardiovascular Intensive Care Unit (CVICU) after their surgery and have had their surgery done through a specific method called median sternotomy. However, people with a body mass index (BMI) over 40, those who refuse to participate, or individuals who have had a lung transplant are not eligible. If you or a loved one qualify for this study, you will have the chance to contribute to important research aimed at improving recovery for heart surgery patients.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age 18 years and older
- • 2. Admitted to Cardiovascular ICU (CVICU) after coronary artery bypass grafting (CABG), isolated valve repair/replacement, or CABG + valve repair/replacement
- • 3. Cardiac surgery performed via median sternotomy
- Exclusion Criteria:
- • 1. BMI\>40
- • 2. Refusal to be consented
- • 3. Prior or current lung transplant patients
About University Of Texas Southwestern Medical Center
The University of Texas Southwestern Medical Center is a leading academic medical institution dedicated to advancing healthcare through innovative research, education, and clinical excellence. With a strong emphasis on translational medicine, the center conducts cutting-edge clinical trials aimed at developing novel therapies and improving patient outcomes across a wide range of diseases. Its multidisciplinary approach leverages a collaborative network of renowned faculty, state-of-the-art facilities, and a commitment to ethical research practices, positioning UT Southwestern at the forefront of medical discovery and patient care.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Dallas, Texas, United States
Patients applied
Trial Officials
Jaffer Odeh, MD
Study Chair
UT Southwestern Medical Center
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials