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Search / Trial NCT04167683

Muscle Dysfunction in Patients With Hematological Diseases Referred to Stem Cell Transplant

Launched by RIGSHOSPITALET, DENMARK · Nov 15, 2019

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Muscle Mass Muscle Strength Complications Patient Reported Outcomes Pro Physical Function Hematopoietic Stem Cell Transplant

ClinConnect Summary

This clinical trial is studying how diseases like leukemia and lymphoma, as well as treatments like stem cell transplants, affect muscle strength and function in patients. Researchers want to understand if muscle problems can give important clues about a patient’s health and treatment decisions. The trial is currently recruiting patients aged 65 to 74 who have been diagnosed with specific blood cancers and are being considered for different types of stem cell transplants.

To be eligible, patients must have certain types of blood cancers and be referred to a stem cell transplant at Rigshospitalet in Denmark. Participants will be asked to undergo tests to check their muscle function and will be monitored throughout the trial. This research aims to help doctors understand how muscle health impacts recovery and treatment outcomes, which could lead to better care for patients with these conditions.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients diagnosed with acute myelogenous leukaemia (AML), acute lymphatic leukaemia (ALL), chronic myelomonocytic leukaemia (CMML), myelodysplastic syndrome (MDS), chronic lymphatic leukaemia (CLL), malignant lymphomas or multiple myeloma (MM) referred to myeloablative HSCT, myeloablative RTC-HSCT or non-myeloablative HSCT at the Department of Haematology, Rigshospitalet, Blegdamsvej.
  • Exclusion Criteria:
  • age \<18; pregnancy; physical or mental disabilities precluding test of muscle function; inability to read and understand Danish

About Rigshospitalet, Denmark

Rigshospitalet, located in Copenhagen, Denmark, is one of the leading hospitals in Scandinavia and a prominent center for clinical research and innovation. As a key academic institution affiliated with the University of Copenhagen, Rigshospitalet is dedicated to advancing healthcare through rigorous clinical trials and groundbreaking research across various medical disciplines. The hospital’s commitment to excellence is reflected in its multidisciplinary approach, collaboration with international research networks, and focus on improving patient outcomes through evidence-based practices. With state-of-the-art facilities and a team of highly qualified professionals, Rigshospitalet plays a crucial role in translating scientific discoveries into effective treatments and therapies.

Locations

Copenhagen, , Denmark

Patients applied

0 patients applied

Trial Officials

Jan Christensen, post doc

Principal Investigator

Department of Occupational- and Physiotherapy, Rigshospitalet

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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