CAES for Internal Hemorrhoids and Rectal Prolapse

Launched by FAMING ZHANG · Nov 16, 2019

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment called cap-assisted endoscopic sclerotherapy (CAES) for people suffering from internal hemorrhoids and rectal prolapse. These conditions can cause discomfort and other issues, and CAES is being explored as a less invasive option that could improve treatment outcomes. The goal of this study is to gather more information about how effective and safe CAES is over the long term.

To participate in this trial, individuals should have grade I to III internal hemorrhoids or rectal prolapse and be prepared for the procedure. However, those with certain conditions, such as severe hemorrhoids, anal issues, or uncontrolled high blood pressure, won't be eligible. If you join the study, you can expect to receive the CAES treatment under careful observation, with the aim of helping researchers understand its benefits and risks better. This research is important for potentially making this new therapy more widely available to patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Grade I-III internal hemorrhoids (with or without external hemorrhoids) or/and recal prolapse.
• • 2. Patients with bowel preparation.
• Exclusion Criteria:
• • 1. History of anoscopic/endoscopic sclerotherapy.
• • 2. Acute thrombotic hemorrhoids or grade IV internal hemorrhoids.
• • 3. Anal stenosis, perianal and perirectal abscess, anal fissure, fistula, fecal incontinence and other severe complications (such as severe anal pain).
• • 4. Inflammatory bowel disease.
• • 5. Full-thickness rectal prolapse through the anus.
• • 6. Acute diarrhea in the past 24 hours.
• • 7. Hypertensive with uncontrolled blood pressure.
• • 8. Cerebrovascular accident.
• • 9. Blood coagulation dysfunction.
• • 10. Pregnant women.
• • 11. Mental disorders.
• • 12. Decompensated cirrhosis.