Comparison of Efficacy of Tranexamic Acid Mesotherapy Versus 0.9% Normal Saline for Melasma

Launched by JINNAH POSTGRADUATE MEDICAL CENTRE · Nov 17, 2019

Keywords

ClinConnect Summary

In this prospective single blind split face controlled trial.Total 30 patients referred to Dermatology Ward were selected. At first, patients were examined under wood lamp for determination of melasma type (epidermal, dermal). Then, patients underwent Tranexamic acid microinjections with a concentration of TA 4 mg/ml with 0.9 % normal saline on their left half of the face and only 0.9%normal saline on their right half of the face, with mesotherapy technique. This procedure was done total of six times with 2-week intervals. Participants were assessed by Hemi Modified Melasma Area and Severit...

Gender

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Eligibility criteria

• Inclusion Criteria:
• • informed consent
• • age between 18 to 55 years
• • bilateral symmetrical mild to severe melasma
• Exclusion Criteria:
• • pregnancy and lactation
• • history of taken any topical treatment for melasma in previous 1 month
• • history of bleeding disorders
• • concomitant use of anticoagulants,
• • any known drug allergy especially to the study drug,
• • having associated medical illnesses.