Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens

Launched by UNIVERSITY HOSPITAL, BASEL, SWITZERLAND · Nov 19, 2019

Keywords

ClinConnect Summary

This clinical trial is focused on creating a shared database to track and understand infections caused by dangerous bacteria and viruses that are resistant to many treatments. These infections can lead to serious health issues and high medical costs, so being able to quickly identify and monitor outbreaks is very important for keeping everyone safe. The study will connect laboratories that work with humans and animals in Switzerland, allowing them to share important information about how these pathogens spread in different places.

To participate in this trial, you need to have either a bacterial or viral infection or colonization. This means that if you have been diagnosed with certain types of bacteria that are hard to treat, like MRSA or those causing tuberculosis, or specific viruses, you may be eligible. Participants will provide samples and information that help researchers analyze the genetic material of these pathogens and understand how they move between people, animals, and the environment. It's important to note that if you do not want your data used for research, you can choose not to participate. Overall, this trial aims to improve our ability to respond to outbreaks of serious infections.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • All patients with either colonisations or infections with either a bacterial or a viral pathogen, where whole genome sequencing data and available minimal epidemiological, demographic and clinical data
• • Pathogens included into analysis are: Multidrug-resistant bacteria include: methicillin resistant Staphylococcus aureus (MRSA), Carbapenemase- and/or extended spectrum betalactamase (ESBL)-producing Enterobacteriaceae and non-fermenting bacteria including Pseudomonas aeruginosa and Acinetobacter baumannii, Vancomycin resistant Enterococcus faecium, and others; virulent bacteria include: Neisseria meningitidis, Neisseria gonorrhoeae, Mycobacterium tuberculosis, Campylobacter spp., Salmonella spp., Legionella pneumophila, Listeria monocytogenes, and Streptococcus pneumoniae, and others; Viruses include: Influenza viruses, Measles virus, Enterovirus E68, Respiratory Syncytial Virus and others.
• Exclusion Criteria:
• • Decline to sign a general consent or any other declining statement against using data for research purposes.