Circulating Non-coding RNA in Acute Ischemic Stroke (AISRNA)

Launched by NANJING FIRST HOSPITAL, NANJING MEDICAL UNIVERSITY · Nov 21, 2019

Keywords

ClinConnect Summary

The AISRNA clinical trial is studying how certain types of non-coding RNA, which are molecules in our cells that do not make proteins, behave in patients who have had an acute ischemic stroke. This type of stroke happens when blood flow to the brain is blocked. Researchers want to find specific patterns of these RNA molecules that could help doctors detect strokes more easily and understand how severe they are. The goal is to see if these RNA types can serve as helpful markers for stroke diagnosis and recovery.

To participate in this study, individuals must be at least 18 years old and have been diagnosed with an acute ischemic stroke within the last 72 hours, confirmed through brain imaging scans. They should also be generally healthy, with no serious prior conditions like bleeding strokes, active cancer, or significant liver or kidney diseases. Participants will undergo tests that involve analyzing their blood for these RNA molecules, which may help improve future stroke treatments and outcomes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 18 years or older
• • Confirmed acute ischemic stroke by a diffusion-weighted imaging-position lesion on magnetic resonance imaging (MRI) and a new lesion on a brain computed tomography (CT) scan
• • Within 72 hours of symptom onset
• • Good performance status
• • Signed an approved informed consents
• Exclusion Criteria:
• • -a history of hemorrhagic infarction, chronic kidney/liver diseases, peripheral arterial occlusive disease, active malignant disease, and inflammatory or infectious diseases