Nasal Inhalation of Isopropyl Alcohol for the Treatment of Nausea in Patients With Cancer

Launched by M.D. ANDERSON CANCER CENTER · Nov 26, 2019

Keywords

ClinConnect Summary

This clinical trial is studying whether inhaling isopropyl alcohol can help reduce nausea in cancer patients. Nausea can be a common and uncomfortable side effect of cancer and its treatments, and this research aims to see if inhalation methods could provide some relief.

To participate in the study, patients must be between 65 and 74 years old, have a cancer diagnosis, and currently experience significant nausea (rated 4 or higher on a scale from 0 to 10). They should also be able to read and write in English and not have received certain medications or treatments in the last 30 minutes. Participants will be asked to inhale isopropyl alcohol and will be monitored for its effects on their nausea. It's important to note that this trial is not yet recruiting participants, so those interested will need to wait for further announcements.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Rate current severity of acute/chronic nausea \>= 4 on NRS (Numeric Rating Scale)
• • Diagnosis of cancer
• • Able to read/write in English
• • Referred to supportive care service as an inpatient or outpatient
• • Rate anxiety as =\< 4 on ESAS-FS (Edmonton Symptom Assessment Scale-Financial Distress and Spiritual Pain)
• • Participants must agree to inhale isopropyl alcohol
• Exclusion Criteria:
• • Received anti-emetics in the last 30 minutes
• • Received medical procedures (e.g. blood draws) which required exposure of isopropyl alcohol in the last 30 minutes
• • Inability to inhale through nares (including recent upper respiratory infection)
• • Known allergy to isopropyl alcohol
• • Delirium (i.e., score \>= 7 on the Memorial Delirium Assessment Scale \[MDAS\])
• • Have never been on anti-emetics during the course of the treatment here (anti-emetic naive)