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Search / Trial NCT04184960

AG & IM in CA Stomach Protocol

Launched by CHINESE UNIVERSITY OF HONG KONG · Dec 1, 2019

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Gastric Cancer Gastroscopy Atrophic Gastritis Intestinal Metaplasia

ClinConnect Summary

This clinical trial, called the AG & IM in CA Stomach Protocol, is looking at how well different methods can predict the risk of developing gastric cancer, which is cancer of the stomach. The study is currently recruiting participants who are 40 years and older and will involve two groups: one group includes patients who have been newly diagnosed with stomach cancer or have a history of high-grade dysplasia (a serious condition that can lead to cancer), while the other group consists of individuals with no previous history of stomach issues.

If you or a family member are interested in participating, you would need to undergo an elective upper gastrointestinal endoscopy, a procedure to look inside the stomach. However, this trial is not for everyone; for example, if someone has had stomach surgery in the past or certain blood disorders, they wouldn't be eligible. Participants can expect to help researchers understand better ways to assess the risk of gastric cancer, potentially leading to improved prevention strategies in the future. Your involvement could be vital in helping improve care for patients at risk of gastric cancer.

Gender

ALL

Eligibility criteria

  • Two groups of patients would be recruited in this case control study.
  • 1. Gastric neoplasia group Patients with newly diagnosed or history of cancer of stomach or gastric high grade dysplasia.
  • 2. Control group Patients with no prior history of gastric dysplasia or cancer
  • Inclusion criteria:
  • 1. Age 40 or above
  • 2. Undergo elective upper gastrointestinal endoscopy
  • Exclusion criteria:
  • 1. Patients with history of gastrectomy
  • 2. Patients with severe thrombocytopenia (Platelet count \<50) or coagulopathy (INR \> 1.5 or on anticoagulation)
  • 3. Contraindication to upper gastrointestinal endoscopy
  • 4. Allergy towards sedative agents (Midazolam / Diazepam) or local anaesthetic spray (Lignocaine)
  • 5. Patients who cannot give informed consent

About Chinese University Of Hong Kong

The Chinese University of Hong Kong (CUHK) is a prestigious research institution renowned for its commitment to advancing medical science and improving healthcare outcomes. As a clinical trial sponsor, CUHK leverages its extensive academic resources and interdisciplinary expertise to conduct innovative research that addresses critical health challenges. The university fosters collaboration among leading researchers, healthcare professionals, and industry partners, ensuring rigorous study design and implementation. CUHK is dedicated to upholding the highest ethical standards in clinical research, with a focus on translating findings into tangible benefits for patients and the broader community.

Locations

Hong Kong, , Hong Kong

Singapore, , Singapore

Osaka, , Japan

Bangkok, , Thailand

Patients applied

0 patients applied

Trial Officials

Hon Chi Yip

Principal Investigator

Chinese University of Hong Kong

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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