MRA and ARB Treatment in Screening of Primary Aldosteronism

Launched by UNIVERSITY HOSPITAL PADOVA · Dec 2, 2019

Keywords

ClinConnect Summary

Primary aldosteronism (PA) is a common form of hypertension caused by aldosterone secretion inappropriate for blood pressure (BP) and volume status. It involves over 11% of the patients referred to specialized hypertension centres, about one fifth of those with drug-resistant hypertension and even a large proportion of the hypertensive patients seen in general practice. The only main subtype of PA that can be unambiguously diagnosed based on post-adrenalectomy using a "five corners" approach is aldosterone-producing adenoma (APA).

In patients undergoing screening for PA the current guideli...

Gender

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Eligibility criteria

• Inclusion Criteria:
• • age 18 - 75 years;
• • diagnosis of Aldosterone Producing Adenoma (APA);
• • written informed consent.
• Exclusion Criteria:
• • refusal to participate to the study;
• • history of intolerance or allergy to canrenone or ARB.