Use of Brain Wave Monitoring During Surgery to Reduce Postoperative Cognitive Dysfunction

Launched by DARTMOUTH-HITCHCOCK MEDICAL CENTER · Dec 4, 2019

Keywords

ClinConnect Summary

This clinical trial is investigating whether monitoring brain wave activity during surgery can help predict the risk of cognitive problems after surgery in patients aged 60 to 80. Postoperative cognitive dysfunction can affect memory and thinking skills, and the researchers want to see if understanding brain activity during anesthesia can help prevent this issue. The study is currently looking for participants who are planning to have elective non-heart surgeries and will stay in the hospital for at least two days.

To be eligible for this trial, participants must be between 60 and 80 years old, speak English as their primary language, and have someone who sees them regularly and can provide support. They also need to be able to give their written consent to join the study. However, individuals with certain severe mental or neurological disorders, substance use issues, or significant sensory impairments will not be able to participate. If you join the study, you will help researchers learn more about how brain activity during surgery can impact recovery, which could lead to better care for older patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 60-80 years of age who present for elective, non-cardiac surgical procedure requiring general anesthesia and an anticipated two-day or longer inpatient hospital stay
• • English as the native and primary language
• • Presence of an informant who has had weekly contact with the participant for at least the last year
• • Participant is capable of providing written informed consent.
• Exclusion Criteria:
• • history of persistent and severe mental illness (e.g., schizophrenia, bipolar disorder)
• • neurological disorder (e.g., Parkinson's disease, epilepsy, stroke)
• • active substance use disorder as defined by the Diagnostic and Statistical Manual Diploma in Social Medicine(DSM-V)
• • history of prior diagnosis of learning disability per the DSM-V
• • estimated premorbid intellectual functioning below a scaled score of 70 based on the Test of Premorbid Functioning (TOPF)
• • severe visual or hearing impairments that prevent the participant from undergoing the neurocognitive assessment.